The S&P Information Technology Index .GSPT dropped 0.9 percent as Apple fell and Jabil Circuit Inc (JBL.N) lost 6.2 percent to $17.38 after UBS cut its price target.

The possibility of a "fiscal cliff" deal not taking place until early 2013 is rising. The back-and-forth negotiations over the fiscal cliff in Washington have kept markets on hold in what would already be a quiet period for stocks.

"We're faced with uncertainty ... and that's going to continue now into January. It basically puts everybody on hold, and (you) just have the markets kind of thrash around," said Larry Abruzzi, senior equity trader at Cabrera Capital Markets Inc in Boston.

President Barack Obama and House of Representatives Speaker John Boehner held a "frank" meeting on Thursday at the White House to discuss how to avoid the tax hikes and spending cuts set to kick in early in 2013.

The S&P 500 dropped 0.6 percent on Thursday after six straight positive sessions. Investors are concerned that going over the cliff could tip the economy back into recession. While a deal is expected to ultimately be reached, a drawn-out debate - like the one seen over 2011's debt ceiling - can erode confidence.

"The markets are not being reactionary right now, though we lost ground yesterday," said Stephen Carl, head equity trader at the Williams Capital Group in New York.

"It doesn't look like anything has been resolved, or is leaning one way or another."

Still, expectations of an eventual agreement have helped the S&P 500 bounce back over the last month, and on Wednesday, the index hit its highest intraday level since late October. For the year, the S&P has advanced more than 12 percent.

The Dow Jones industrial average .DJI slipped 24.09 points, or 0.18 percent, to 13,146.63. The Standard & Poor's 500 Index .SPX lost 4.81 points, or 0.34 percent, to 1,414.64. The Nasdaq Composite Index .IXIC fell 15.50 points, or 0.52 percent, to 2,976.66.

Best Buy Co Inc (BBY.N) slid 15.5 percent to $11.93 after the electronics retailer agreed to extend the deadline for the company's founder to make a bid. Shares jumped as much as 19 percent on Thursday after initial reports of a bid this week from founder Richard Schulze.

Consumer prices fell in November for the first time in six months, indicating U.S. inflation pressures were muted. A separate report showed manufacturing grew at its swiftest pace in eight months in December.

Data out of China was encouraging, as Chinese manufacturing grew at its fastest pace in 14 months in December. The news was seen as helping U.S. materials companies, including U.S. Steel (X.N), which rose 6.3 percent to $23.73.